Thomas E Witzig Selected Research

Dexamethasone (Maxidex)

11/2018	Phase 1 study of pomalidomide and dexamethasone for relapsed/refractory primary CNS or vitreoretinal lymphoma.
8/2018	Bendamustine and rituximab (BR) versus dexamethasone, rituximab, and cyclophosphamide (DRC) in patients with Waldenström macroglobulinemia.
1/2018	A phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma.
10/2017	Long-term follow-up of chemoimmunotherapy with rituximab, oxaliplatin, cytosine arabinoside, dexamethasone (ROAD) in patients with relapsed CD20+ B-cell non-Hodgkin lymphoma: Results of a study of the Mayo Clinic Cancer Center Research Consortium (MCCRC) MC0485 now known as academic and community cancer research united (ACCRU).
10/2017	Dexamethasone, rituximab and cyclophosphamide for relapsed and/or refractory and treatment-naïve patients with Waldenstrom macroglobulinemia.
5/2017	A phase 2 study of lenalidomide, rituximab, cyclophosphamide, and dexamethasone (LR-CD) for untreated low-grade non-Hodgkin lymphoma requiring therapy.
11/2016	Randomized phase 2 trial of ixazomib and dexamethasone in relapsed multiple myeloma not refractory to bortezomib.
1/2016	Reduction in C-reactive protein indicates successful targeting of the IL-1/IL-6 axis resulting in improved survival in early stage multiple myeloma.
8/2011	Lenalidomide, cyclophosphamide and dexamethasone (CRd) for newly diagnosed multiple myeloma: results from a phase 2 trial.
2/2010	Lenalidomide plus dexamethasone versus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients.

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Thomas E Witzig Research Topics

Disease

84	Neoplasms (Cancer) 05/2024 - 02/2002
65	Lymphoma (Lymphomas) 05/2024 - 01/2002
63	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2023 - 01/2002
38	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 05/2022 - 07/2007
35	Multiple Myeloma 01/2021 - 11/2002
26	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2024 - 06/2002
19	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 11/2023 - 05/2005
19	Waldenstrom Macroglobulinemia (Macroglobulinemia) 01/2022 - 01/2002
18	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 04/2024 - 11/2002
13	Disease Progression 01/2020 - 09/2002
12	Infections 05/2024 - 06/2002
12	Hodgkin Disease (Hodgkin's Disease) 01/2024 - 10/2005
12	Immunoglobulin Light-chain Amyloidosis 06/2014 - 02/2003
11	B-Cell Lymphoma (Lymphoma, B Cell) 04/2024 - 01/2002
10	Thrombocytopenia (Thrombopenia) 08/2017 - 06/2002
7	Neutropenia 05/2022 - 01/2007
5	Fatigue 05/2022 - 04/2005
5	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 04/2003
5	Colonic Neoplasms (Colon Cancer) 03/2007 - 09/2003
4	Acute Kidney Injury (Acute Renal Failure) 02/2024 - 09/2021
4	Febrile Neutropenia 05/2022 - 07/2005
4	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 07/2006
4	Immunoglobulin G4-Related Disease 12/2018 - 06/2015
4	Anemia 08/2017 - 01/2003
4	Necrosis 01/2017 - 10/2003
4	Smoldering Multiple Myeloma 01/2016 - 08/2004
4	Paraproteinemias (Monoclonal Gammopathy) 12/2012 - 01/2002
4	Autoimmune Diseases (Autoimmune Disease) 01/2011 - 09/2003
4	Carcinoma (Carcinomatosis) 03/2007 - 05/2002
3	Sepsis (Septicemia) 04/2021 - 06/2002
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2018 - 09/2007
3	T-Cell Lymphoma (Lymphoma, T Cell) 07/2015 - 10/2009
3	Genetic Translocation (Chromosomal Translocation) 01/2015 - 09/2013
3	POEMS Syndrome (Syndrome, POEMS) 07/2013 - 04/2003
3	Chromosome Aberrations (Chromosome Abnormalities) 02/2011 - 05/2003
3	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 04/2008 - 06/2004
2	COVID-19 04/2024 - 06/2023
2	Diarrhea 05/2022 - 03/2013

Drug/Important Bio-Agent (IBA)

53	Rituximab (Mabthera)FDA Link 01/2024 - 01/2002
24	Lenalidomide (CC 5013)FDA Link 01/2022 - 01/2007
23	Proteins (Proteins, Gene)FDA Link 04/2024 - 04/2003
21	ibritumomab tiuxetan (Zevalin)FDA Link 01/2023 - 02/2002
16	Dexamethasone (Maxidex)FDA LinkGeneric 11/2018 - 11/2002
13	CytokinesIBA 04/2024 - 08/2004
11	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 08/2011
11	TOR Serine-Threonine KinasesIBA 01/2019 - 08/2005
11	Everolimus FDA Link 10/2018 - 07/2006
10	Immunoglobulin M (IgM)IBA 01/2020 - 01/2002
10	Monoclonal AntibodiesIBA 10/2008 - 08/2003
9	Biomarkers (Surrogate Marker)IBA 07/2022 - 12/2006
8	Methotrexate (Mexate)FDA LinkGeneric 02/2024 - 06/2004
8	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 12/2005
8	Immunoglobulins (Immunoglobulin)IBA 11/2018 - 04/2006
8	Thalidomide (Thalomid)FDA Link 10/2010 - 11/2002
7	Yttrium-90IBA 01/2023 - 08/2002
7	Prednisone (Sone)FDA LinkGeneric 01/2021 - 10/2011
7	YttriumIBA 07/2013 - 02/2002
6	ibrutinibIBA 10/2021 - 01/2017
6	Vincristine (Oncovin)FDA LinkGeneric 01/2021 - 12/2005
6	Cyclin D1IBA 10/2020 - 08/2005
6	Bortezomib (Velcade)FDA Link 01/2020 - 07/2005
6	Mechanistic Target of Rapamycin Complex 1IBA 10/2018 - 10/2009
6	temsirolimus FDA Link 04/2011 - 08/2005
5	AnthracyclinesIBA 04/2024 - 08/2014
5	B-Cell Activating FactorIBA 05/2009 - 02/2006
4	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 06/2002
4	Immune Checkpoint InhibitorsIBA 01/2024 - 03/2016
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 09/2006
4	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2019 - 07/2006
4	LigandsIBA 01/2017 - 02/2008
4	Sirolimus (Rapamycin)FDA Link 03/2012 - 07/2006
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2012 - 08/2004
4	MTOR InhibitorsIBA 04/2011 - 10/2009
4	CD20 AntigensIBA 03/2008 - 01/2006
3	Messenger RNA (mRNA)IBA 01/2023 - 08/2005
3	Bendamustine Hydrochloride FDA Link 01/2022 - 08/2018
3	InterferonsIBA 01/2022 - 09/2012
3	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 04/2021 - 03/2007
3	TroponinIBA 01/2019 - 09/2004
3	SteroidsIBA 12/2018 - 03/2008
3	Immunoglobulin G (IgG)IBA 04/2016 - 03/2008
3	Alemtuzumab (Campath)FDA Link 01/2015 - 08/2003
3	Complement System Proteins (Complement)IBA 09/2012 - 10/2008
3	Vitamin D FDA LinkGeneric 07/2012 - 09/2010
3	Interleukin-12 (IL 12)IBA 04/2012 - 01/2002
3	Interleukin-10 (Interleukin 10)IBA 03/2012 - 10/2009
3	Interleukin-6 (Interleukin 6)IBA 11/2011 - 10/2003
3	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2010 - 05/2003
3	Phosphotransferases (Kinase)IBA 08/2008 - 05/2003
2	Biological FactorsIBA 01/2024 - 09/2012
2	Radioisotopes (Radionuclides)IBA 08/2023 - 07/2011
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2022 - 11/2012

Therapy/Procedure

89	Therapeutics 05/2024 - 01/2002
27	Radioimmunotherapy 01/2024 - 02/2002
23	Drug Therapy (Chemotherapy) 01/2022 - 06/2002
11	Stem Cell Transplantation 01/2022 - 12/2002
8	Radiotherapy 05/2024 - 12/2003
7	Aftercare (After-Treatment) 02/2024 - 04/2003
6	Immunotherapy 01/2024 - 05/2002
3	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 04/2006 - 05/2004